Rph3a Mouse shRNA Plasmid (Locus ID 19894)
Specifications
| Product Data | |
| Locus ID | 19894 |
|---|---|
| Synonyms | 2900002P20Rik; AU022689; AW108370 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Rph3a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 19894). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC042585, BC050883, NM_001302344, NM_001302345, NM_011286, NM_011286.1, NM_011286.2, NM_011286.3, NM_001302344.1, NM_001302345.1 |
| UniProt ID | P47708 |
| Summary | Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Plays also a role in the exocytosis of arginine vasopressin hormone (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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