Fbxo45 Mouse shRNA Plasmid (Locus ID 268882)
Specifications
| Product Data | |
| Locus ID | 268882 |
|---|---|
| Synonyms | 2610017J04Rik; AI463119; BC026799 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Fbxo45 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 268882). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC026799, BC088738, BC098203, NM_173439, NM_173439.1, NM_173439.2 |
| UniProt ID | Q8K3B1 |
| Summary | Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration. Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway. Specifically recognizes TP73, promoting its ubiquitination and degradation (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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