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Met Mouse shRNA Plasmid (Locus ID 17295)

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SKU
TL513769
Met - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
4 Weeks*

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Specifications
Specifications
Product Data
Locus ID 17295
Synonyms AI838057; c-Met; HGF; HGFR; Par4
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Met - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 17295). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_008591, NM_008591.1, NM_008591.2, BC117969, BC117970, BC128481, BC128482, BC156287
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

ICAM-1 promotes cancer progression by regulating SRC activity as an adapter protein in colorectal cancer
Lim, Kang, Kim et al
Cell Death Dis (2022) 13 (4), 417 DOI: 10.1038/s41419-022-04862-1
Cited by 42
AI Summary: In this study, OriGene products, including the ICAM-1 Human cDNA ORF Clone (Cat# RC200249) and ICAM-1 shRNA plasmids (Cat# TG311931), were used to manipulate ICAM-1 expression in colorectal cancer cells, enabling investigation of its role in promoting cancer progression through regulation of SRC activity.
FigureFigureFigure
FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation
Park, Choi, Ko et al
Cancer Res Treat (2017)
AI Summary: OriGene’s pGFP-V-RS plasmid vectors containing MET shRNA were used in this study to stably silence MET expression, enabling the authors to investigate the role of MET in acquired lapatinib resistance in HER2-positive gastric cancer cells.
Snippet: 9. MET silencing by stable transfection with shRNA plasmid vector For MET silencing, the pGFP-V-RS plasmid vectors containing either scrambled shRNA or MET shRNA were purchased from OriGene (Rockville, MD, USA). The sequence of MET ... Cite SaveSaving
Showing 1-2 of 2 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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