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Eef1a1 Mouse shRNA Plasmid (Locus ID 13627)

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SKU
TL513283
Eef1a1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 13627
Synonyms MGC7551; MGC8115; MGC8209; MGC18758; MGC27859; MGC102592; MGC103271; MGC118397
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Eef1a1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 13627). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC004005, BC004067, BC005660, BC018223, BC018485, BC083069, BC092053, BC092276, BC095965, BC108391, NM_010106, NM_010106.1, NM_010106.2, BC003969, BC040689, BC050124, BC068258, BC092292, BC099609
UniProt ID P10126
Summary This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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Documents
Resources

file-alt Citations

EEF1A1 deacetylation enables transcriptional activation of remyelination
Duman, Vaquié, Nocera et al
Nat Commun (2020) 11 (1), 3420 DOI: 10.1038/s41467-020-17243-z
Cited by 57
AI Summary: OriGene products, specifically the pCMV6-AC-mouse eEF1A1-turbo GFP (C-ter) and GFP backbone constructs, were used to express and study the role of eEF1A1 in the regulation of remyelination in this research.
Snippet: perimental animals (10 theophylline-treated mice and 9 vehicle-treated mice). Constructs Expression constructs: pCMV6-AC-mouse eEF1A1-turbo GFP (C-ter) and GFP backbone constructs were acquired from Origene. Control shRNA (PLKO) and Stat3 shRNA (SHCLNG-NM_011486, TRCN0000071456) were acquired from Sigma-Aldrich. Sox10 wild type and mutant constructs, 95, MIC and HMG and the Mbp promoter-lucifera
FigureFigureFigure
Showing 1-1 of 1 papers.
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