Cd300a Mouse shRNA Plasmid (Locus ID 217303)
Specifications
| Product Data | |
| Locus ID | 217303 |
|---|---|
| Synonyms | B230315M08Rik; Clm8; LMIR1; MAIR-I; MAIR-Ia; mcpir1; MMAC8; Pigr4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Cd300a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 217303). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001347654, NM_170758, NM_001359812, NM_170758.1, NM_170758.2, NM_170758.3, BC139296, BC139297, NM_170758.4 |
| UniProt ID | Q6SJQ0 |
| Summary | Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:12874256, PubMed:12893283, PubMed:16339535). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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