Gata3 Mouse shRNA Plasmid (Locus ID 14462)

SKU
TL513036
Gata3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 14462
Synonyms Gata-3; jal
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Gata3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 14462). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC062915, NM_008091, NM_001355110, NM_001355111, NM_001355112, NM_008091.1, NM_008091.2, NM_008091.3
UniProt ID P23772
Summary Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
Kalim, Yang, Wunderlich et al
J Immunother Cancer (2022) 10 (11) DOI: 10.1136/jitc-2022-004806
Cited by 28
AI Summary: OriGene products, including scrambled shRNA (TR30021), CAI shRNA (TL510087), and GATA3 shRNA (TL513036) lentiviral vectors, were used to generate shRNA lentiviruses for gene knockdown experiments to investigate the molecular mechanisms underlying Treg cell instability and antitumor immunity in this study.
Snippet: hRNA-mediated knockdown, scrambled shRNA, CAI shRNA, and GATA3 shRNA lentiviral supernatants were produced by transfection of 293T cells with packaging lentiviral plasmids and either scrambled shRNA (Origene, TR30021), CAI shRNA (Origene, TL510087) or GATA3 shRNA (Origene, TL513036) lentiviral vectors followed by concentrating with Lenti-X concentrator (Takara, 631231). The viral supernatants were;For lentiviral shRNA-mediated knockdown, scrambled shRNA, CAI shRNA, and GATA3 shRNA lentiviral supernatants were produced by transfection of 293T cells with packaging lentiviral plasmids and either scrambled shRNA (Origene, TR30021), CAI shRNA (Origene, TL510087) or GATA3 shRNA (Origene,
FigureFigureFigure
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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