Iqgap1 Mouse shRNA Plasmid (Locus ID 29875)
Specifications
| Product Data | |
| Locus ID | 29875 |
|---|---|
| Synonyms | AA682088; D7Ertd237e; D7Ertd257e; mKIAA0051 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Iqgap1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 29875). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC046385, NM_016721, NM_016721.1, NM_016721.2, BC022105, BC037685 |
| UniProt ID | Q9JKF1 |
| Summary | Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity (PubMed:16968698). It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth. May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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