Nox4 Mouse shRNA Plasmid (Locus ID 50490)
Specifications
| Product Data | |
| Locus ID | 50490 |
|---|---|
| Synonyms | AI648021 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Nox4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 50490). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001285833, NM_001285835, NM_015760, NM_015760.1, NM_015760.2, NM_015760.3, NM_015760.4, NM_015760.5, NM_001285835.1, BC138918, BC021378, BC145462, BC165954 |
| UniProt ID | Q9JHI8 |
| Summary | Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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