Mecp2 Mouse shRNA Plasmid (Locus ID 17257)
Specifications
| Product Data | |
| Locus ID | 17257 |
|---|---|
| Synonyms | 1500041B07Rik; D630021H01Rik; Mbd5; WBP10 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Mecp2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 17257). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC027153, NM_001081979, NM_010788, NM_010788.1, NM_010788.2, NM_010788.3, NM_010788.4, NM_001081979.1, NM_001081979.2 |
| UniProt ID | Q9Z2D6 |
| Summary | Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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