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Prdx1 Mouse shRNA Plasmid (Locus ID 18477)

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SKU
TL512119
Prdx1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 18477
Synonyms MSP23; NkefA; OSF-3; OSF3; PAG; Paga; PrdxI; prx1; PrxI; Tdpx2; TDX2; TPxA
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Prdx1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 18477). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC083348, BC086648, NM_011034, NM_011034.1, NM_011034.2, NM_011034.3, NM_011034.4
UniProt ID P35700
Summary Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (PubMed:19766572).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Peroxiredoxin 1 protein interacts with influenza virus ribonucleoproteins and is required for efficient virus replication
Dai, Li, Roller
Vaccine (2018) 36 (30), 4540-4547 DOI: 10.1016/j.vaccine.2018.05.125
AI Summary: OriGene products, specifically the Hush 29mer shRNA constructs against Prdx-1 mRNA (Catalog number TG302287) and control shRNA constructs, were used to knock down Prdx-1 expression and assess its role in influenza virus replication in this study.
Snippet: matrixscience.com). 2.5. Plasmid and cell lines. Hush 29mer shRNA constructs against Prdx-1 mRNA in pGEF-V-RS vector (Catalog number TG302287) and control shRNA constructs were purchased from OriGene. In order
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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