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Clasp2 Mouse shRNA Plasmid (Locus ID 76499)

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SKU
TL512086
Clasp2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 76499
Synonyms 1500004F14Rik; 8030404L10Rik; C77448; CLASP2beta; mKIAA0627
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Clasp2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 76499). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC117963, BC117964, BC131791, BC131792, NM_001081960, NM_001114347, NM_001286599, NM_001286600, NM_001286601, NM_001286602, NM_001286603, NM_029633, NM_001114347.1, NM_001081960.1, NM_029633.1, NM_029633.2, NM_001286603.1, NM_001286599.1, NM_001286601.1, NM_001286600.1, NM_001286602.1, BC026688, BC030468, BC141415
UniProt ID Q8BRT1
Summary Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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