Tufm Mouse shRNA Plasmid (Locus ID 233870)
Specifications
| Product Data | |
| Locus ID | 233870 |
|---|---|
| Synonyms | 2300002G02Rik; C76308; C76389; EF-TuMT; EFTU |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Tufm - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 233870). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC060959, BC100596, NM_001163713, NM_172745, NM_001163713.1, NM_172745.1, NM_172745.2, NM_172745.3 |
| UniProt ID | Q8BFR5 |
| Summary | Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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