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Sox9 Mouse shRNA Plasmid (Locus ID 20682)

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SKU
TL511411
Sox9 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Specifications
Specifications
Product Data
Locus ID 20682
Synonyms 2010306G03Rik; AV220920; mKIAA4243
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Sox9 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 20682). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC023796, BC023808, BC023953, BC024958, BC034264, NM_011448, NM_011448.1, NM_011448.2, NM_011448.3, NM_011448.4, BC004064
UniProt ID Q04887
Summary Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development (PubMed:20940257, PubMed:28263186). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (PubMed:20940257).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
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file-alt Citations

Sox9 regulates the luminal stem/progenitor cell properties of salivary glands
Tanaka, Mabuchi, Hata et al
Exp Cell Res (2019) 382 (1), 111449 DOI: 10.1016/j.yexcr.2019.05.030
Cited by 25
AI Summary: OriGene products contributed to this study by providing the Sox9 shRNA lentiviral particles (Cat# TL502431) and the Sox9 antibody (Cat# TA801606), which were used to manipulate and detect Sox9 expression in salivary gland stem/progenitor cells.
Oncogenicity of the developmental transcription factor Sox9
Matheu, Collado, Wise et al
Cancer Res. (2012) 72 (5), 1301-15 DOI: 10.1158/0008-5472.CAN-11-3660
Cited by 14
AI Summary: OriGene’s SOX9 shRNAs (sh1 and sh75) were used to knock down SOX9 expression in cells, enabling the authors to study the effects of SOX9 depletion on tumorigenic properties in their investigation of SOX9’s role in cancer.
Snippet: by short hairpin RNA (shRNA), cells were transfected using Lipofectamine (Invitrogen), according to instructions of the reagent supplier. Cells were cultivated in the presence of puromycin for 3 weeks. Cells were transfected using 2 different SOX9 shRNAs (OriGene;sh1 or sh75
Showing 1-2 of 2 papers.
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