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Nod1 Mouse shRNA Plasmid (Locus ID 107607)

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SKU
TL511305
Nod1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 107607
Synonyms C230079P11; Card4; F830007N14Rik; Nlrc1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Nod1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 107607). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC042670, NM_001171007, NM_172729, NM_001171007.1, NM_172729.1, NM_172729.2, NM_172729.3, BC043670
UniProt ID Q8BHB0
Summary Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Recruits NLRP10 to the cell membrane following bacterial infection (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Cdx2 expression and intestinal metaplasia induced by H. pylori infection of gastric cells is regulated by NOD1-mediated innate immune responses
Asano, Imatani, Watanabe et al
Cancer Res. (2016)
AI Summary: In this study, OriGene’s mouse NOD1-shRNA vector and scrambled shRNA vector were used to generate stable gastric cell lines with reduced NOD1 expression, enabling the authors to investigate the role of NOD1 in regulating Cdx2 expression and intestinal metaplasia during H. pylori infection.
Snippet: Establishment of NOD1-knocked down stable cell line. GSM06 cells were transfected with mouse NOD1-shRNA vector (Origene), using a 4D-Nucleofector Page 10. - 10 - ... Puromycin (Thermo Scientific). Vector with non-effective scrambled shRNA (Origene) was used ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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