Tspan15 Mouse shRNA Plasmid (Locus ID 70423)
Specifications
| Product Data | |
| Locus ID | 70423 |
|---|---|
| Synonyms | 1110036D12Rik; 2700063A19Rik; AW048364; Tm4sf15 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Tspan15 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 70423). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC003872, NM_197996, NM_197996.1, NM_197996.2 |
| UniProt ID | F7BWT7 |
| Summary | Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:23035126, PubMed:26668317). Promotes ADAM10-mediated cleavage of (CDH2) (PubMed:26668317). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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