Mcrs1 Mouse shRNA Plasmid (Locus ID 51812)
Specifications
| Product Data | |
| Locus ID | 51812 |
|---|---|
| Synonyms | C78274; ICP22BP; MSP58; P78 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Mcrs1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 51812). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC003746, BC085099, BC108340, NM_001164156, NM_016766, NM_016766.1, NM_016766.2, NM_016766.3, NM_001164156.1 |
| UniProt ID | Q99L90 |
| Summary | Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity. Binds to G-quadruplex structures in mRNA. Binds to RNA homopolymer poly(G) and poly(U).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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