Fblim1 Mouse shRNA Plasmid (Locus ID 74202)
Specifications
| Product Data | |
| Locus ID | 74202 |
|---|---|
| Synonyms | 2410043F08Rik; Cal; Fblp1; Gt10; migfilin; migfilin(s) |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Fblim1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 74202). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC004777, NM_001163256, NM_133754, NM_133754.1, NM_133754.2, NM_133754.5, NM_001163256.1, BM946176 |
| UniProt ID | Q71FD7 |
| Summary | Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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