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Sept6 Mouse shRNA Plasmid (Locus ID 56526)

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SKU
TL509453
Sept6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 56526
Synonyms 2810035H17Rik; C920001C06Rik; mKIAA0128; Sep6
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Sept6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 56526). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC010489, NM_001177323, NM_001177324, NM_001253706, NM_019942, NR_033443, NM_001359140, NM_001359141, NM_001359142, NM_019942.1, NM_019942.2, NM_019942.3, NM_019942.4, NM_019942.5, NM_001177323.1, NM_001177323.2, NM_001177324.1, NM_001253706.1, BM245544
UniProt ID Q9R1T4
Summary Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Mapping axon initial segment structure and function by multiplexed proximity biotinylation
Hamdan, Lim, Torii et al
Nat Commun (2020) 11 (1), 100 DOI: 10.1038/s41467-019-13658-5
Cited by 112
AI Summary: OriGene products Ndel1C and Trim46 were used as DNA templates to generate fusion constructs for proximity biotinylation experiments, enabling the mapping of axon initial segment (AIS) molecular organization in this study.
Snippet: d NF186∆FIGQY were amplified by PCR from Rat NF186 tagged with an N-terminal HA epitope tag53. pENTR11-hENO2-Ndel1C-Myc-BirA* and pENTR11-hENO2-Myc-BirA*-Ndel1C were generated by amplifying Ndel1C (Origene) and inserting it into shuttle template pENTR11-hENO2-MCS-BirA*-MCS. pENTR11-hENO2-Trim46∆C -Myc-BirA* and pENTR11-hENO2-Myc-BirA*- Trim46∆C were generated by amplifying Trim46 (Origene) a
FigureFigureFigure
Showing 1-1 of 1 papers.
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