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Cdh11 Mouse shRNA Plasmid (Locus ID 12552)

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SKU
TL509242
Cdh11 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
In Stock*

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Other products for "Cdh11 or NM_009866"

Specifications
Specifications
Product Data
Locus ID 12552
Synonyms Cad1; Cad11; OB-cad; OSF-4
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Cdh11 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 12552). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC046314, NM_009866, NM_009866.1, NM_009866.2, NM_009866.3, NM_009866.4, NM_009866.5
UniProt ID P55288
Summary This gene encodes a type II classical cadherin and preproprotein that is proteolytically processed to generate a mature protein product. This protein product is an integral membrane protein that mediates calcium-dependent cell-cell adhesion, specifically in the context of bone development. Homozygous knockout mice for this gene exhibit impaired synovium development and reduced bone density. Multiple pseudogenes of this gene have been identified in the genome. provided by RefSeq, Aug 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Epigenetic disruption of cadherin-11 in human cancer metastasis
Carmona, Villanueva, Vidal et al
J. Pathol. (2012) 228 (2), 230-40 DOI: 10.1002/path.4011
Cited by 65
AI Summary: OriGene’s shRNA vectors targeting CDH11 were used to silence CDH11 expression in SIHN011A cells, enabling the study to demonstrate the role of CDH11 in inhibiting tumor growth and metastasis.
Snippet: SIHN011A cells were transfected with short-hairpin RNA (shRNA) vectors (Origene), specifically targeting the CDH11 mRNA sequence and Scramble ... In a similar manner, CDH11 expression reduced the lung-metastatic potential and represented a good prognostic factor in
FigureFigureFigure
Showing 1-1 of 1 papers.
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