Plat Mouse shRNA Plasmid (Locus ID 18791)
Specifications
| Product Data | |
| Locus ID | 18791 |
|---|---|
| Synonyms | AU020998; AW212668; D8Ertd2; D8Ertd2e; t; t-; tPA |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Plat - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 18791). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC011256, BC057967, BC061508, NM_008872, NM_008872.1, NM_008872.2, NM_008872.3 |
| UniProt ID | P11214 |
| Summary | This gene encodes a key enzyme of the fibrinolytic pathway. The encoded protein undergoes proteolytic processing by plasmin to generate a heterodimeric serine protease that cleaves the proenzyme plasminogen to produce plasmin, a protease that is required to break down fibrin clots. Additionally, the encoded protein is involved in other biological processes such as synaptic plasticity, cell migration and tissue remodeling. Mice lacking the encoded protein display a reduction in long-term potentiation in hippocampus and conversely, transgenic mice overexpressing the encoded protein have increased and prolonged long-term potentiation. provided by RefSeq, Jul 2015 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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