Sh3pxd2b Mouse shRNA Plasmid (Locus ID 268396)
Specifications
| Product Data | |
| Locus ID | 268396 |
|---|---|
| Synonyms | fad49; G431001E03Rik; TSK4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Sh3pxd2b - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 268396). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_177364, NM_177364.1, NM_177364.2, NM_177364.3, BC141306, BC020358, BC115711, BC115764, NM_177364.4 |
| UniProt ID | A2AAY5 |
| Summary | Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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