Noxa1 Mouse shRNA Plasmid (Locus ID 241275)

SKU
TL507338
Noxa1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 241275
Synonyms NY-CO-31; SDCCAG31
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Noxa1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 241275). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC047532, NM_001163626, NM_172204, NM_172204.1, NM_172204.2, NM_172204.3, NM_172204.4, NM_001163626.1
UniProt ID Q8CJ00
Summary Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Obatoclax interacts synergistically with the irreversible proteasome inhibitor carfilzomib in GC- and ABC-DLBCL cells in vitro and in vivo
Dasmahapatra, Lembersky, Son et al
Mol. Cancer Ther. (2012) 11 (5), 1122-32 DOI: 10.1158/1535-7163.MCT-12-0021
Cited by 6
AI Summary: OriGene's HuSH 29 mer short hairpin RNA (shRNA) construct against NOXA1 (catalog no. TF311134) was used in this study to knock down NOXA expression in SUDHL4 cells, enabling the authors to investigate the role of NOXA in the apoptotic response to combined carfilzomib and obatoclax treatment.
Snippet: HuSH 29 mer short hairpin RNA (shRNA) constructs against NOXA1 in a pRFP-C-RS vector from Origene Technologies, (catalog no TF311134) were used to knockdown NOXA in SUDHL4 cells through transient transfection.
Showing 1-1 of 1 papers.
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