Ttll6 Mouse shRNA Plasmid (Locus ID 237930)
Specifications
| Product Data | |
| Locus ID | 237930 |
|---|---|
| Synonyms | 4932418K24Rik; D11Moh43e; D11Moh44e; t8130b59 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Ttll6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 237930). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC132203, NM_172799, NM_172799.1, NM_172799.2, NM_172799.3, NM_172799.4, BC138058, BC145130, BC145131 |
| UniProt ID | A4Q9E8 |
| Summary | Polyglutamylase which preferentially modifies alpha-tubulin (PubMed:17499049, PubMed:21074048). Mediates tubulin polyglutamylation in cilia (PubMed:22246503). Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (PubMed:17499049, PubMed:21074048). Generates long side-chains (PubMed:20530212). Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS (PubMed:26829768).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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