Kctd13 Mouse shRNA Plasmid (Locus ID 233877)
Specifications
| Product Data | |
| Locus ID | 233877 |
|---|---|
| Synonyms | 1500003N18Rik; AV259508; Pdip1; PDIP1alpha; Poldip1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Kctd13 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 233877). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC079607, NM_172747, NM_172747.1, NM_172747.2 |
| UniProt ID | Q8BGV7 |
| Summary | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission (PubMed:29088697). The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and promoting synaptic transmission (PubMed:29088697).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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