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Mrgprd Mouse shRNA Plasmid (Locus ID 211578)

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SKU
TL506324
Mrgprd - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 211578
Synonyms Gm499; Mgrd; MrgD; TGR7
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Mrgprd - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 211578). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_203490, NM_203490.1, NM_203490.2, NM_203490.3, BC137948, BC137950
UniProt ID Q91ZB8
Summary May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein-coupled receptor D
Bautzova, Hockley, Perez-Berezo et al
Sci Signal (2018) 11 (561) DOI: 10.1126/scisignal.aal2171
AI Summary: In this study, OriGene’s Mrgprd expression plasmid was used to transfect cells, enabling investigation of the receptor’s role in mediating 5-oxoETE-induced neuronal hypersensitivity relevant to IBS-C.
Snippet: OriGene Technologies), with GeneJuice (Millipore, USA) transfection reagent. Cells were incubated overnight at 37°C and 5% CO2 before the medium was replaced with 18 ml of OptiMEM (Gibco, USA)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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