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Itgb4 Mouse shRNA Plasmid (Locus ID 192897)

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SKU
TL506190
Itgb4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 192897
Synonyms AA407042; C230078O20; CD104
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Itgb4 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 192897). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001005608, NM_133663, NM_001005608.1, NM_001005608.2, NM_133663.1, NM_133663.2, BC006632, BC025194, BC038607, BC059192, BC080751
Summary Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Rare variant analysis in multiply affected families, association studies and functional analysis suggest a role for the ITGΒ4 gene in schizophrenia and bipolar disorder
O'Brien, Fiorentino, Curtis et al
Schizophr. Res. (2018)
AI Summary: OriGene contributed to this study by providing the TrueORF Gold ITGB4 plasmid with a C-terminal Myc-DDK tag (catalog number RC220541), which was used to investigate the functional effects of ITGB4 gene variants in cell-based assays.
Snippet: passaged beyond passage 25. 2.8. ITGB4 plasmid constructs. A TrueORF gold ITGB4 plasmid with a c-terminal Myc-DDK tag was obtained from Origene (RC220541, Origene Technologies, Rockville, MD, USA). The ITGB4 genetic
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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