Pdzd8 Mouse shRNA Plasmid (Locus ID 107368)
Specifications
| Product Data | |
| Locus ID | 107368 |
|---|---|
| Synonyms | A630041P07Rik; AV329468; AW228944; Pdzk8 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Pdzd8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 107368). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001033222, NM_001033222.1, NM_001033222.2, NM_001033222.3, BC141370, BC031591, BC141371 |
| UniProt ID | B9EJ80 |
| Summary | Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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