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Cemip Mouse shRNA Plasmid (Locus ID 80982)

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SKU
TL505378
Cemip - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 80982
Synonyms 12H19.01.T7; 6330404C01Rik; 9930013L23Rik; AY007814; Kiaa1199
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Cemip - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 80982). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC115873, BC116643, NM_030728, NM_030728.1, NM_030728.2, NM_030728.3, NM_030728.4, BC056981, BC086772
UniProt ID Q8BI06
Summary Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination
Su, Matsumoto, Banine et al
Glia (2019) 68 (2), 263-279 DOI: 10.1002/glia.23715
AI Summary: OriGene contributed to this study by providing the CEMIP (NM_030728) Mouse Tagged ORF Clone and the pCMV6-Entry Tagged Cloning Vector, which were used to generate expression vectors for investigating the role of CEMIP in oligodendrocyte maturation and remyelination.
Snippet: al., 2014). 2.4 Generation of expression vectors. The CEMIP expression vector and control vector were purchased from Origene (Cemip (NM_030728) Mouse Tagged ORF Clone;pCMV6‐Entry Tagged Cloning Vector). The;- al., 2014). 2.4 Generation of expression vectors. The CEMIP expression vector and control vector were purchased from Origene (Cemip (NM_030728) Mouse Tagged ORF Clone
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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