Med8 Mouse shRNA Plasmid (Locus ID 80509)
Specifications
| Product Data | |
| Locus ID | 80509 |
|---|---|
| Synonyms | 2210021A15Rik; AB041805; ARC32 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Med8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 80509). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC021870, NM_001290688, NM_020000, NM_173719, NM_020000.1, NM_020000.2, NM_020000.3, NM_173719.1, NM_173719.2, NM_173719.3, NM_001290688.1, BC002315, BC051683, BC053738 |
| UniProt ID | Q9D7W5 |
| Summary | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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