Htra3 Mouse shRNA Plasmid (Locus ID 78558)
Specifications
| Product Data | |
| Locus ID | 78558 |
|---|---|
| Synonyms | 2210021K23Rik; 9530081K03Rik; Prsp; Tasp |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Htra3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 78558). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001042615, NM_030127, NM_030127.1, NM_030127.2, NM_030127.3, NM_001042615.1, NM_001042615.2, BC138588, BC022646, BC056216, BC138587 |
| UniProt ID | Q9D236 |
| Summary | Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (PubMed:15206957). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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