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Arid2 Mouse shRNA Plasmid (Locus ID 77044)

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SKU
TL505226
Arid2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 77044
Synonyms 1700124K17Rik; 4432409D24Rik; zipzap/p200
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Arid2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 77044). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC027180, NM_175251, NM_175251.1, NM_175251.2, NM_175251.3, NM_175251.4
UniProt ID E9Q7E2
Summary Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression
Xu, Flowers, Moran
J. Biol. Chem. (2012) 287 (7), 5033-41 DOI: 10.1074/jbc.M111.279968
Cited by 3
AI Summary: OriGene’s ARID2 shRNA plasmids (pRS vectors containing ARID2 shRNA-encoding sequences) and scrambled control were used to stably deplete ARID2 in MC3T3-E1 cells, enabling the study of ARID2's role in tissue-specific gene expression during osteoblast differentiation.
Snippet: To generate stable ARID2-depleted cell lines, MC3T3-E1 cells were transfected with pRS vectors containing ARID2 shRNA-encoding sequences or a scrambled sequence purchased from OriGene (Rockville, MD) and selected with puromycin (4 μg/ml).
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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