Dcstamp Mouse shRNA Plasmid (Locus ID 75766)
Specifications
| Product Data | |
| Locus ID | 75766 |
|---|---|
| Synonyms | 4833414I07Rik; DC-STAMP; FIND; mDC-STAMP; Tm7sf4 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Dcstamp - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 75766). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001289506, NM_001289508, NM_001289512, NM_001289513, NM_029422, NM_029422.1, NM_029422.2, NM_029422.3, NM_029422.4, NM_001289512.1, NM_001289513.1, NM_001289508.1, NM_001289506.1, BC139146, BC145557, BC145558 |
| UniProt ID | Q7TNJ0 |
| Summary | Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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