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March8 Mouse shRNA Plasmid (Locus ID 71779)

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SKU
TL504615
March8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 71779
Synonyms 1300017E09Rik; M; Marc; MARCH-VIII; March8; Mir
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components March8 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 71779). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC050908, BC053090, NM_001302383, NM_001302384, NM_001302385, NM_027920, NM_027920.1, NM_027920.2, NM_027920.3, NM_027920.4, NM_027920.5, NM_001302385.1, NM_001302383.1, NM_001302384.1
UniProt ID Q9DBD2
Summary The protein encoded by this gene is a member of the membrane-associated really interesting new gene-CH family of proteins. These proteins are E3 ubiquitin-protein ligases that modulate antigen presentation by downregulating major histocompatibility complex class II surface expression through endocytosis. The transcript is primarily expressed by dendritic cells and macrophages. Overexpression of this gene in antigen presenting cells results in immune defective phenotypes, including resistance to autoimmune disease onset. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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