Steap3 Mouse shRNA Plasmid (Locus ID 68428)
Specifications
| Product Data | |
| Locus ID | 68428 |
|---|---|
| Synonyms | 1010001D01Rik; pHyde; Tsap6 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Steap3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 68428). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC037435, NM_001085409, NM_133186, NM_001085409.1, NM_133186.1, NM_133186.2, NM_133186.3, BC027251, NM_133186.4 |
| UniProt ID | Q8CI59 |
| Summary | Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Also mediates reduction of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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