Mfn1 Mouse shRNA Plasmid (Locus ID 67414)
Specifications
| Product Data | |
| Locus ID | 67414 |
|---|---|
| Synonyms | 2310002F04Rik; 6330416C07Rik; D3Ertd265e; HR2; mKIAA4032 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Mfn1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67414). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC056641, NM_024200, NM_024200.1, NM_024200.2, NM_024200.3, NM_024200.4, BC002133, BC008137, BC047050 |
| UniProt ID | Q811U4 |
| Summary | Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:12527753, PubMed:23921378, PubMed:24513856, PubMed:15297672). Membrane clustering requires GTPase activity (By similarity). It may involve a major rearrangement of the coiled coil domains (PubMed:15297672). Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:12527753). Overexpression induces the formation of mitochondrial networks (in vitro). Has low GTPase activity (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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