Pi4k2b Mouse shRNA Plasmid (Locus ID 67073)
Specifications
| Product Data | |
| Locus ID | 67073 |
|---|---|
| Synonyms | 2610042N09Rik; 4933409G22Rik |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Pi4k2b - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 67073). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC062144, NM_025951, NM_028744, NM_025951.1, NM_025951.2, NM_025951.3, NM_028744.1, NM_028744.2, NM_028744.3, BC010257 |
| UniProt ID | Q8CBQ5 |
| Summary | Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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