Rbfox3 Mouse shRNA Plasmid (Locus ID 52897)

SKU
TL502927
Rbfox3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 52897
Synonyms Fox-3; Hrnbp3; NeuN; Neuna60
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Rbfox3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 52897). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC054403, NM_001024931, NM_001039167, NM_001039168, NM_001285436, NM_001285437, NM_001285438, NM_001039167.1, NM_001039168.1, NM_001024931.1, NM_001024931.2, NM_001285438.1, NM_001285437.1, NM_001285436.1
UniProt ID Q8BIF2
Summary Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development
Kim, Nam, Mukouyama et al
J. Cell Biol. (2013) 200 (4), 443-58 DOI: 10.1083/jcb.201206146
Cited by 128
AI Summary: OriGene products contributed to this study by providing the Numb expression plasmids (Numb cDNA clones), which were used to analyze the effects of specific Numb splice isoforms on neuronal differentiation.
Snippet: The top and bottom bands represent Numb-12in and Numb-12ex proteins, respectively. Each band most likely represents two proteins that include and exclude the 11 aa encoded by exon 6 but are not resolved under these electrophoresis conditions.
FigureFigureFigure
Showing 1-1 of 1 papers.
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