Ppp2r1a Mouse shRNA Plasmid (Locus ID 51792)
Specifications
| Product Data | |
| Locus ID | 51792 |
|---|---|
| Synonyms | 6330556D22Rik; PP2A; PR65 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Ppp2r1a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 51792). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC006606, BC052678, NM_016891, NM_016891.1, NM_016891.2, NM_016891.3 |
| UniProt ID | Q76MZ3 |
| Summary | The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit (PubMed:10100624). Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT (By similarity). Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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