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Amot Mouse shRNA Plasmid (Locus ID 27494)

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SKU
TL502714
Amot - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 27494
Synonyms CAG-2; D0Kist1; Sii6
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Amot - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 27494). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC057638, NM_001290274, NM_153319, NM_153319.1, NM_153319.2, NM_153319.3, NM_001290274.1, BC057638.1
UniProt ID Q8VHG2
Summary Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression
Hsu, Hung, Chou et al
Oncogene (2014)
Cited by 85
AI Summary: OriGene products contributed to this study by providing the pCMV-AMOT (p130) plasmid for AMOT overexpression and the Lung Cancer cDNA Array I for measuring AMOT levels in lung cancer tissues.
Snippet: For AMOT (p130) overexpression, cells were transfected with pCMV or pCMV-AMOT (p130) plasmid (Origene, Rockville, MD, USA).The stable clones were established by treatment with G418. ... The AMOT level in Lung Cancer cDNA Array I (Origene) was also measured ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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