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Grk6 Mouse shRNA Plasmid (Locus ID 26385)

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SKU
TL502586
Grk6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 26385
Synonyms Gprk6
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Grk6 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 26385). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC075719, NM_001038018, NM_001112711, NM_001286063, NM_001286064, NM_001286065, NM_001286066, NM_011938, NM_001112711.1, NM_001112711.2, NM_011938.1, NM_011938.2, NM_011938.3, NM_011938.4, NM_001038018.1, NM_001038018.2, NM_001038018.3, NM_001038018.4, NM_001286066.1, NM_001286065.1, NM_001286063.1, NM_001286064.1, BC057206, NM_001286066.2, NM_011938.5
UniProt ID O70293
Summary Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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