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Mapk7 Mouse shRNA Plasmid (Locus ID 23939)

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SKU
TL502521
Mapk7 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Other products for "Mapk7 or NM_001291033"

Specifications
Specifications
Product Data
Locus ID 23939
Synonyms BMK-1; BMK1; ERK-5; ERK5; Erk5-T; PRKM7
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Mapk7 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23939). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC100398, NM_001291033, NM_001291034, NM_001291035, NM_001291036, NM_001291037, NM_011841, NM_011841.1, NM_011841.2, NM_001291035.1, NM_001291036.1, NM_001291037.1, NM_001291033.1, NM_001291034.1, BC013745, BC033598, BC051020, BC058096, BC082315, NM_001361989
UniProt ID Q9WVS8
Summary Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression (By similarity). Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction (By similarity).UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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