Adamts5 Mouse shRNA Plasmid (Locus ID 23794)
SKU
TL502481
Adamts5 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 23794 |
|---|---|
| Synonyms | 9530092O11Rik; ADAM-; ADAM-TS5; ADAMTS1; ADAMTS11; ADMP-2; AI481094; ASMP-2 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Adamts5 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 23794). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_011782, NM_011782.1, NM_011782.2, BC138619, BC138620 |
| UniProt ID | Q9R001 |
| Summary | This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent aggrecanase enzyme. Mice lacking the encoded protein are protected from surgery-induced osteoarthritis and antigen-induced arthritis. provided by RefSeq, May 2016 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Lost expression of ADAMTS5 protein associates with progression and poor prognosis of hepatocellular carcinoma
Li, Xiong, Yang et al
Drug Des Devel Ther (2015) 9, 1773-83 DOI: 10.2147/DDDT.S77069
Li, Xiong, Yang et al
Drug Des Devel Ther (2015) 9, 1773-83 DOI: 10.2147/DDDT.S77069
AI Summary: In this study, OriGene’s ADAMTS5 cDNA (Cat# RC209825) was used to stably transfect HCC cells, enabling the researchers to investigate the effects of ADAMTS5 overexpression on tumor growth, angiogenesis, and VEGF expression both in vitro and in vivo.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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