Scn8a Mouse shRNA Plasmid (Locus ID 20273)
Specifications
| Product Data | |
| Locus ID | 20273 |
|---|---|
| Synonyms | AI853486; C630029C19Rik; dmu; med; mnd-2; mnd2; NaCh6; Nav1.6; nmf2; nmf58; nmf335; nur14; seal |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Scn8a - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 20273). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001077499, NM_011323, NM_011323.1, NM_011323.2, NM_011323.3, NM_001077499.1, BC099466 |
| Summary | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages, isoform 5 may participate in the control of podosome and invadopodia formation.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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