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Nr4a2 Mouse shRNA Plasmid (Locus ID 18227)

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SKU
TL501521
Nr4a2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 18227
Synonyms HZF-3; NOT; Nurr1; RNR-1; TINOR; TINUR
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Nr4a2 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 18227). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001139509, NM_013613, NM_013613.1, NM_013613.2, NM_001139509.1, BC137715, BC144854
UniProt ID Q06219
Summary Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

NURR1 and ERR1 Modulate the Expression of Genes of a DRD2 Coexpression Network Enriched for Schizophrenia Risk
Torretta, Rampino, Basso et al
J. Neurosci. (2020) 40 (4), 932-941 DOI: 10.1523/JNEUROSCI.0786-19.2019
AI Summary: OriGene products, including Mouse Lenti-ORF Nr4a2 and Esrra viral vectors as well as 29mer shRNA constructs for Nr4a2 and Esrra, were used to overexpress or knockdown these transcription factors in neuronal cultures, enabling the study of their regulatory effects on schizophrenia-associated gene networks.
Snippet: Plasmids Mouse Lenti-ORF Nr4a2 and Esrra viral vectors were purchased from Origene. As a negative control, mCherry sequence was subcloned within the same Lentiviral vector backbone (mCherry vector). Mouse 4unique 29mer shRNA constructs in lentiviral GFP vector for Nr4a2 and Esrra, were used for KD experiments, with the relative scrambled negative control (Scramble;Origene). Cell lines
Showing 1-1 of 1 papers.
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