Mcl1 Mouse shRNA Plasmid (Locus ID 17210)
SKU
TL501318
Mcl1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
2 Weeks*
Specifications
| Product Data | |
| Locus ID | 17210 |
|---|---|
| Synonyms | AW556805; Mcl-1 |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Mcl1 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 17210). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC003839, BC005427, BC021638, NM_008562, NM_008562.1, NM_008562.2, NM_008562.3 |
| UniProt ID | P97287 |
| Summary | Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 2 has antiapoptotic activity.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
FTY720 Induces Autophagy-Associated Apoptosis in Human Oral Squamous Carcinoma Cells, in Part, through a Reactive Oxygen Species/Mcl-1-Dependent Mechanism
Bai, Chiu, Chiu et al
Sci Rep (2017) 7 (1), 5600 DOI: 10.1038/s41598-017-06047-9
Bai, Chiu, Chiu et al
Sci Rep (2017) 7 (1), 5600 DOI: 10.1038/s41598-017-06047-9
AI Summary: In this study, the Mcl-1 plasmid from OriGene was used to investigate the role of Mcl-1 overexpression in modulating FTY720-induced apoptosis and autophagy in oral squamous carcinoma cells.
Snippet: Sigma-Aldrich (St. Louis, MO). The GFP-LC3 plasmid was purchased from Addgene (Cambridge, MA). Mcl-1 plasmid was obtained from OriGene Technologies, Inc. (Rockville, MD). The enhanced chemiluminescence system ... All 5 versions Cite SaveSaving...;;... Sigma-Aldrich (St. Louis, MO). The GFP-LC3 plasmid was purchased from Addgene (Cambridge, MA). Mcl-1 plasmid was obtained from OriGene Technologies...
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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