Cd47 Mouse shRNA Plasmid (Locus ID 16423)
SKU
TL501123
Cd47 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 16423 |
|---|---|
| Synonyms | 9130415E20Rik; AA407862; AI848868; AW108519; B430305P08Rik; IAP; Itgp |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Cd47 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 16423). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC012667, NM_010581, NM_010581.1, NM_010581.2, NM_010581.3, BC009094, NM_001368415, NM_001368416, NM_001368417, NM_001368418 |
| UniProt ID | Q61735 |
| Summary | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity).UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Targeting cluster of differentiation 47 improves the efficacy of anti-cytotoxic T-lymphocyte associated protein 4 treatment via antigen presentation enhancement in pancreatic ductal adenocarcinoma
Song, Lu, Xu
Exp Ther Med (2020) 20 (4), 3301-3309 DOI: 10.3892/etm.2020.9054
Song, Lu, Xu
Exp Ther Med (2020) 20 (4), 3301-3309 DOI: 10.3892/etm.2020.9054
Cited by 11
AI Summary: OriGene products, including lentiviral vectors (cat. no. MR204706L1) and CD47 shRNA (cat. no. TL501123), were used to manipulate CD47 expression in cell models, enabling the study of CD47's role in antigen presentation and immune response in pancreatic ductal adenocarcinoma.
Snippet: All vectors used were lentiviral vectors purchased from OriGene Technologies, Inc. On day 1, a total of 1.2x107 293 cells (cat. no no. MR204706L1;OriGene Technologies, Inc.), CD47 shRNA (cat. no. TL501123;OriGene Technologies, Inc.) or control vector (cat. no
High expression of CD47 predicts adverse prognosis in Chinese patients and suppresses immune response in melanoma
Fu, Li, Zhang et al
Biomed Pharmacother (2017) 93, 1190-1196 DOI: 10.1016/j.biopha.2017.06.030
Fu, Li, Zhang et al
Biomed Pharmacother (2017) 93, 1190-1196 DOI: 10.1016/j.biopha.2017.06.030
Cited by 30
Showing 1-2 of 2 papers.
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