Il4ra Mouse shRNA Plasmid (Locus ID 16190)
Specifications
| Product Data | |
| Locus ID | 16190 |
|---|---|
| Synonyms | CD124; Il4r |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Il4ra - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 16190). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC112911, NM_001008700, NM_001008700.2, NM_001008700.3, BC012309, BC128301, BC128302, NM_010557, NM_001363983, NM_001008700.4 |
| UniProt ID | P16382 |
| Summary | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.UniProtKB/Swiss-Prot Function |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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