Gapdh Mouse shRNA Plasmid (Locus ID 14433)

SKU
TL500768
Gapdh - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
4 Weeks*
Specifications
Specifications
Product Data
Locus ID 14433
Synonyms Ga; Gapd
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Gapdh - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 14433). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq BC083065, BC083079, BC083080, BC083149, BC085274, BC085275, BC085315, BC091768, BC092252, BC092264, BC092267, BC092294, BC093508, BC094037, BC095932, BC096042, BC096440, BC096590, BC110311, NM_001289726, NM_008084, NM_008084.1, NM_008084.2, NM_008084.3, NM_001289726.1, BC091768.1, BC096042.1, BC020407, BC023196, BC091736, BC145810, BC145812
UniProt ID P16858
Summary This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein was originally identified as a key glycolytic enzyme that converts D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Subsequent studies have assigned a variety of additional functions to the protein including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Alternative splicing results in multiple transcript variants. Many pseudogenes similar to this locus are found throughout the mouse genome. provided by RefSeq, Jan 2014
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists
Ganapathy-Kanniappan, Kunjithapatham, Torbenson et al
Radiology (2012) 262 (3), 834-45 DOI: 10.1148/radiol.11111569
Cited by 47
AI Summary: OriGene Technologies contributed GAPDH-specific shRNA and control shRNA, which were used to inhibit GAPDH expression and assess tumor response in the human hepatocellular carcinoma mouse model described in the paper.
Snippet: Tumor growth in vivo and its response to percutaneous injection of GAPDH inhibitors (3-bromopyruvate [3-BrPA] or GAPDH short hairpin RNA [shRNA]) was monitored by using ... GAPDH-specific shRNA and control shRNA were obtained (OriGene Technologies, Rockville,
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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