Drd5 Mouse shRNA Plasmid (Locus ID 13492)

SKU
TL500555
Drd5 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*
Specifications
Specifications
Product Data
Locus ID 13492
Synonyms D5R; Drd-5; Drd1b; Gpcr1
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components Drd5 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 13492). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_013503, NM_013503.1, NM_013503.2, NM_013503.3, BC138060, BC138059
UniProt ID Q8BLD9
Summary Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.UniProtKB/Swiss-Prot Function
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

Dopamine Uses the DRD5-ARRB2-PP2A Signaling Axis to Block the TRAF6-Mediated NF-κB Pathway and Suppress Systemic Inflammation
Wu, Hu, Wang et al
Mol Cell (2020) 78 (1), 42-56.e6 DOI: 10.1016/j.molcel.2020.01.022
Cited by 95
AI Summary: In this study, OriGene products including anti-DRD5 antibody (Cat# TA326312) and ARRB2 shRNA plasmid (Cat# TL308642) were used to investigate the role of dopamine signaling in macrophages, enabling the authors to elucidate how the DRD5-ARRB2-PP2A axis suppresses inflammation by blocking the TRAF6-mediated NF-κB pathway.
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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