Dmpk Mouse shRNA Plasmid (Locus ID 13400)
Specifications
| Product Data | |
| Locus ID | 13400 |
|---|---|
| Synonyms | DM; Dm15; DMK; MDPK; MT-PK |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | Dmpk - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 13400). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | BC024150, BC075715, NM_001190490, NM_001190491, NM_032418, NR_126095, NM_001190491.1, NM_032418.1, NM_032418.2, NM_001190490.1, BC056615, NM_001190490.2, NM_001190491.2, NM_032418.3 |
| UniProt ID | P54265 |
| Summary | The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appears to play a role in myogenesis. In adults, the transcript is localized to several tissues including brain, heart, and skeletal and smooth muscle, and a function in cytoskeletal remodeling has been described. Transcripts with expanded CUG repeats in the 3' untranslated region mediate alternative splicing of several genes and sequester RNA binding proteins and RNA transcripts that contain CAG repeats, resulting in myotonic dystrophy, an autosomal dominant neuromuscular disorder. Alternative splicing results in multiple protein coding and non-coding transcript variants. provided by RefSeq, Oct 2014 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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